Tab Article

• 300 case studies.

•  Based on the new CBME curriculum allowing horizontal, spiral, vertical, and nested integration.

•  Full coverage of all chapters of biochemistry with complete clinical correlations.

•  Illustrations of clinical cases in sections, namely history, physical examination, laboratory workup, and questions related to the diagnosis of the case. This will help sharpen clinical skills.

•  Each case study ends up in a clinical note and a short summary, titled Clinical Pearls.

•  Many alternative unsolved case studies (72) have been provided at the end of the book.

•  A detailed description of molecular and biochemical techniques, including electrophoresis; chromatography; western blotting; southern blotting; polymerase chain reaction; enzyme?linked immunosorbent assay (ELISA); colorimetry, and newborn screening.

•  Case?based multiple?choice questions for self?assessment (with answers).

•  Quick revisions (summary charts): Acid?base imbalance; disorders of amino acid metabolism; disorders of carbohydrate metabolism; regulatory mechanisms of carbohydrate metabolism; disorders of lipid metabolism; regulatory mechanisms of lipid metabolism; electrolyte imbalance; clinical implications of vitamin deficiencies, and clinically important hemoglobinopathies.

•  Nine new case studies including?clinical role of ribonucleotide reductase, tumor markers, enzyme action and inhibition, functions and significance of zinc and selenium, and heavy metal toxicity.

•  Pictures (37 new pictures), tables, and flowcharts for meaningful explanations of content details.