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The use of cord blood as a source of hematopoietic stem cell transplantation has steadily increased since the first cord blood transplant 11 years ago. This text reviews the molecular and cellular biology of cord blood, the collection and processing of cord blood units, the clinical potential of ex vivo expansion, and concludes with a discussion of cord blood banking and matching, and the ethical and legal issues related to blood cell therapy and transplantation.
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