9780367490812

Genetics and genomics in medicine


by Tom Strachan, Anneke Lucassen
Publisher: CRC Press
ISBN:9780367490812
Year:2023
Edition: 2nd
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The second edion of this textbook wrien for undergraduate students, graduate students and medical researchers, Genecs and Genomics in Medicine explains the science behind the uses of genecs and genomics in medicine today, and how it is being applied. Maintaining the features that made the first edion so popular, this second edion has been thoroughly updated in line with the latest developments in the field. DNA technologies are explained, with emphasis on the modern techniques that are revoluonizing the use of genec informaon in medicine and indicang the role of genecs in common diseases. Epigenecs and non-coding RNA are covered in-depth as are genec approaches to treatment and prevenon, including pharmacogenomics, genec tesng, and personalized medicine. A dedicated chapter charts the latest insights into the molecular basis of cancers, cancer genomics and novel approaches to cancer detecon. Coverage of genec tesng at the level of genes, chromosomes and genomes has been significantly expanded and updated. Extra prominence has been given to addional genomic analyses, ethical aspects, and novel therapeuc approaches. Various case studies illustrate selected clinical applicaons.

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