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An authoritative survey of the scientific background for therapeutic cancer vaccines, the challenges to their development, and their current uses in treating cancer. The authors examine the basic issues that affect all vaccines (such as immune adjuvants and prime-boost strategies), describe the methods for antigen discovery, and review the preclinical development phases for each major vaccine strategy. They also spell out the clinical results for cancer vaccines now beginning to be used in the treatment of many common cancers.
Morse offers this text to introduce this field of study to seasoned researchers and those new to the field. The book is well laid out into four sections including a Basic Science Background, General Vaccine and Immunotherapy Strategies, Tumor-Specific Vaccines Being Developed and closing with a final section on General Background of Clinical Trials and Immune Analysis.
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Sanjiv Kapoor
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